Gut microbiota and colon cancer: the carbohydrate link

Summary: Carbohydrates account for about half of the daily caloric intake of adults on a western-style diet, and previous studies have linked carbohydrate-rich diets to colorectal cancer in humans

Belcheva A, Martin A. Gut microbiota and colon cancer: the carbohydrate link. Mol Cell Oncol. 2014;2(1):e969630. Published 2014 Nov 11. doi:10.4161/23723548.2014.969630


Understanding the complex pathophysiology of colorectal cancer and the interaction between host genetics, the gut microbiome, and diet has attracted significant attention in the last few years. The discovery that gut microbial metabolites may dictate the course of colorectal cancer progression supports the development of microbial-targeted strategies.